The role of misinformation in the spread of the anti-vaccine movement: A descriptive study.
PDF

Keywords

Vaccination
Misinformation
Vaccine Hesitancy
Public Health
Latin America

How to Cite

Martínez Centeno, A. A., & Romina Leardi, M. (2025). The role of misinformation in the spread of the anti-vaccine movement: A descriptive study. SAP Primary Care, 1, 15. https://doi.org/10.62486/pc202515

Abstract

Background: Misinformation is a growing phenomenon that undermines confidence in immunization, a key factor in the rise of the anti-vaccine movement. This study aimed to evaluate the attitudes, practices, and level of exposure to vaccine misinformation among parents in Latin America. Material and methods: An observational, cross-sectional, and descriptive design was used. The sample was non-probabilistic and purposive, consisting of 117 participants from Latin America, who completed a structured online survey. Results: Ninety-two percent of adults expressed a favorable attitude toward vaccination; however, 41% of parents reported partial or total noncompliance with childhood vaccinations. Forty-two percent of participants expressed doubt or uncertainty about the vaccines offered. The primary source of information was the doctor or pediatrician (72%). The predominant reasons for hesitancy were fear of adverse effects (33%) and distrust of pharmaceutical companies (29%). Conclusion: Misinformation is a factor that generates significant vaccine hesitancy among the population, even among highly educated individuals. Although healthcare professionals are the most reliable source, partial noncompliance persists, underscoring the need to strengthen risk communication with transparency and scientific evidence.

PDF

References

1. Larson HJ, Jarrett C, Eckersberger E, Smith DM, Paterson P. Understanding vaccine hesitancy around vaccines and vaccination from a global perspective: a systematic review of published literature, 2007–2012. Vaccine. 2014;32(19):2150–9. doi:10.1016/j.vaccine.2014.01.081.

2. Betsch C, Schmid P, Heinemeier D, Korn L, Holtmann C, Böhm R. Beyond confidence: Development of a measure assessing the 5C psychological antecedents of vaccination. PLoS One. 2018;13(12):e0208601. doi:10.1371/journal.pone.0208601.

3. Nyhan B, Reifler J, Richey S, Freed GL. Effective Messages in Vaccine Promotion: A Randomized Trial. Pediatrics. 2014;133(4):e835–42. doi:10.1542/peds.2013-2365.

4. Kata A. Anti-vaccine activists, web 2.0, and the postmodern paradigm – An overview of tactics and tropes used online by the anti-vaccination movement. Vaccine. 2012;30(25):3778–89. doi:10.1016/j.vaccine.2011.11.112.

5. Dubé E, Gagnon D, MacDonald NE. Strategies intended to address vaccine hesitancy: Review of published reviews. Vaccine. 2015;33(34):4191–203. doi:10.1016/j.vaccine.2015.04.041.

6. Wilson SL, Wiysonge C. Social media and vaccine hesitancy. BMJ Glob Health. 2020;5(10):e004206. doi:10.1136/bmjgh-2020-004206.

7. Betsch C. How behavioural science data helps mitigate the COVID-19 crisis. Nat Hum Behav. 2020;4(5):438. doi:10.1038/s41562-020-0866-1.

8. Chou WS, Gaysynsky A, Vanderpool RC. The Social Media Vaccine Hesitancy Report. Hum Vaccin Immunother. 2021;17(9):3116–22. doi:10.1080/21645515.2021.1888633.

9. Cinelli M, Quattrociocchi W, Galeazzi A, Valensise CM, Brugnoli E, Schmidt AL, et al. The COVID-19 social media infodemic. Sci Rep. 2020;10(1):16598. doi:10.1038/s41598-020-73510-5.

10. Johnson NF, Velásquez N, Restrepo NJ, Leahy R, Gabriel N, El Oud S, et al. The online competition between pro- and anti-vaccination views. Nature. 2020;582(7811):230–3. doi:10.1038/s41586-020-2281-1.

11. World Health Organization. Managing the COVID-19 infodemic: Promoting healthy behaviors and mitigating the harm from misinformation and disinformation. Geneva: World Health Organization; 2020.

12. Fridman A, Gershon R, Gneezy A. COVID-19 and vaccine hesitancy: A longitudinal study. PLoS One. 2021;16(4):e0250123. doi:10.1371/journal.pone.0250123.

13. Ropero-Álvarez AM, Landaverde R, Pincus LB. Where We Go From Here: Health Misinformation on Social Media. Rev Panam Salud Publica. 2021;45:e58. doi:10.26633/RPSP.2021.58.

14. Barrera-Cruz L, Rosas-Magallanes C, Rodríguez-Vargas M, Orozco-Vargas L. Vaccine hesitancy: A review to address the phenomenon in Latin America. Rev Colomb Anestesiol. 2021;49(1):e974. doi:10.5554/22562088.e974.

15. Fadda M, D’Agostino M, Forlanini D, Nobile M, Cappa C, Gualano MR. Prevalence of health misinformation on social media: systematic review. J Med Internet Res. 2021;23(1):e17187. doi:10.2196/17187.

16. Viana I da S, Cursino EG, Miranda P da S, Silva LF da, Machado MED. Vaccine hesitancy of parents and family members of children and the control of immunopreventable diseases. Rev Bras Enferm. 2023;76(Suppl 2):e20220261. doi:10.1590/0034-7167-2022-0261.

17. Wilson S, Caccamise K, Valcarce F, Kruk ME, Pardo S, Gómez G, et al. Barriers and facilitators to vaccination

18. in Latin America: a thematic synthesis of qualitative studies. Cad Saude Publica. 2024;40(6):e00165023. doi:10.1590/0102-311X00165023.

19. Abram G, Egon A. Health misinformation on social media: consequences for public health policy. Int J Health Policy Manag. 2024;13(1):e272. doi:10.34172/ijhpm.2024.27

20. Banas JA, Bessarabova E, Penkauskas MC, Talbert N. Inoculating Against Anti-Vaccination Conspiracies. Health Commun 2024;39:1760–8. https://doi.org/10.1080/10410236.2023.2235733.

21. Benoit SL, Mauldin RF. The “anti-vax” movement: a quantitative report on vaccine beliefs and knowledge across social media. BMC Public Health 2021;21:2106. https://doi.org/10.1186/s12889-021-12114-8.

22. Durach F, Buturoiu R, Craiu D, Cazacu C, Bargaoanu A. Crisis of confidence in vaccination and the role of social media. Eur J Paediatr Neurol 2022;36:84–92. https://doi.org/10.1016/j.ejpn.2021.12.009.

23. GBD 2023 Demographics Collaborators. Global age-sex-specific all-cause mortality and life expectancy estimates for 204 countries and territories and 660 subnational locations, 1950-2023: a demographic analysis for the Global Burden of Disease Study 2023. Lancet 2025;406:1731–810. https://doi.org/10.1016/S0140-6736(25)01330-3.

24. GBD 2023 Disease and Injury and Risk Factor Collaborators. Burden of 375 diseases and injuries, risk-attributable burden of 88 risk factors, and healthy life expectancy in 204 countries and territories, including 660 subnational locations, 1990-2023: a systematic analysis for the Global Burden of Disease Study 2023. Lancet 2025;406:1873–922. https://doi.org/10.1016/S0140-6736(25)01637-X.

25. Glasper EA. Reducing the Impact of Anti-Vaccine Propaganda on Family Health. Compr Child Adolesc Nurs 2021;44:79–85. https://doi.org/10.1080/24694193.2021.1912988.

26. Klimiuk K, Czoska A, Biernacka K, Balwicki Ł. Vaccine misinformation on social media - topic-based content and sentiment analysis of Polish vaccine-deniers’ comments on Facebook. Hum Vaccin Immunother 2021;17:2026–35. https://doi.org/10.1080/21645515.2020.1850072.

27. Larson HJ, Broniatowski DA. Volatility of vaccine confidence. Science 2021;371:1289. https://doi.org/10.1126/science.abi6488.

28. Maciuszek J, Polak M, Stasiuk K, Doliński D. Active pro-vaccine and anti-vaccine groups: Their group identities and attitudes toward science. PLoS One 2021;16:e0261648. https://doi.org/10.1371/journal.pone.0261648.

29. Mills MC, Sivelä J. Should spreading anti-vaccine misinformation be criminalised? BMJ 2021;372:n272. https://doi.org/10.1136/bmj.n272.

30. Nguyen A, Catalan-Matamoros D. Anti-Vaccine Discourse on Social Media: An Exploratory Audit of Negative Tweets about Vaccines and Their Posters. Vaccines (Basel) 2022;10:2067. https://doi.org/10.3390/vaccines10122067.

31. Oliveira IS de, Cardoso LS, Ferreira IG, Alexandre-Silva GM, Jacob B de C da S, Cerni FA, et al. Anti-vaccination movements in the world and in Brazil. Rev Soc Bras Med Trop 2022;55:e05922021. https://doi.org/10.1590/0037-8682-0592-2021.

32. Peters MDJ. Addressing vaccine hesitancy and resistance for COVID-19 vaccines. Int J Nurs Stud 2022;131:104241. https://doi.org/10.1016/j.ijnurstu.2022.104241.

33. Ransing R, Dashi E, Rehman S, Chepure A, Mehta V, Kundadak GK. COVID-19 anti-vaccine movement and mental health: Challenges and the way forward. Asian J Psychiatr 2021;58:102614. https://doi.org/10.1016/j.ajp.2021.102614.

34. Smith SE, Sivertsen N, Lines L, De Bellis A. Decision making in vaccine hesitant parents and pregnant women - An integrative review. Int J Nurs Stud Adv 2022;4:100062. https://doi.org/10.1016/j.ijnsa.2022.100062.

35. Spaull RV, Kurian MA. SLC6A3-Related Dopamine Transporter Deficiency Syndrome. In: Adam MP, Bick S, Mirzaa GM, Pagon RA, Wallace SE, Amemiya A, editors. GeneReviews®, Seattle (WA): University of Washington, Seattle; 1993.

36. Tayloe DT. Immunization Messaging, Communication, and Outreach Amidst the Growing Anti-vaccine Movement. N C Med J 2021;82:118–21. https://doi.org/10.18043/ncm.82.2.118.

37. Westhoff M-A, Posovszky C, Debatin K-M. How to Respond to Misinformation From the Anti-Vaccine Movement. Inquiry 2023;60:469580231155723. https://doi.org/10.1177/00469580231155723.

38. Wolynn T, Hermann C, Hoffman BL. Social Media and Vaccine Hesitancy: Help Us Move the Needle. Pediatr Clin North Am 2023;70:329–41. https://doi.org/10.1016/j.pcl.2022.11.010.

39. Immunology shines in the dark. Nat Rev Immunol 2021;21:193–4. https://doi.org/10.1038/s41577-021-00527-w.

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Copyright (c) 2025 Alonso Alejandro Martínez Centeno, María Romina Leardi (Author)