Ectopic pregnancy treated with Methotrexate, case report
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Keywords

Ectopic Pregnancy
Methotrexate
Treatment

How to Cite

Chávez Moya, M. O., Saez Puig, L. T., Cepero González, A., Cepero Peña, R., Córdova Guillén, D. D., Chirino Yanes, D., & Hernández Cabrera, L. (2026). Ectopic pregnancy treated with Methotrexate, case report. SAP Primary Care, 2, 98. https://doi.org/10.62486/pc202698

Abstract

Introduction: ectopic pregnancy is defined as the implantation of a fertilized egg outside the uterus, representing a potentially life-threatening condition. The most common location is the fallopian tube, although other sites such as the cervix or cesarean scars are also possible. Despite diagnostic and therapeutic advances, disparities in access to care persist. The condition has significant physical, emotional, and reproductive consequences. Diagnosis has improved with transvaginal ultrasound and ẞ-hCG measurement, and treatment has evolved from open surgery to medical options like methotrexate.

Case report: a 29-year-old woman presented with pelvic pain, metrorrhagia, and mild hemodynamic instability. Transvaginal ultrasound and ẞ-hCG levels confirmed a tubal ectopic pregnancy. Intramuscular methotrexate was administered, followed by clinical and hormonal monitoring. The patient showed favorable progression, with decreasing ẞ-hCG levels and complete resolution without complications. She received reproductive counseling and emotional support.

Conclusions: methotrexate proved effective in an uncomplicated ectopic pregnancy. Proper patient selection, strict follow-up, and a comprehensive approach that includes emotional care are key to successful management. Evidence supports this conservative medical treatment as a safe and effective alternative.

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References

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This work is licensed under a Creative Commons Attribution 4.0 International License.

Copyright (c) 2026 Maikro Osvaldo Chávez Moya, Liz Thalía Saez Puig, Arianny Cepero González, Roxana Cepero Peña, Daniela Dignorah Córdova Guillén, Danay Chirino Yanes, Leodanis Hernández Cabrera (Author)